Archive for the 'Pharmacology' Category

Mechanism of Cialis action

October 25th, 2007

 
Although Viagra, Levitra, and Cialis all work by inhibition of PDE5, tadalafil’s distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the “weekend pill.” This longer half-life also [...]

Viagra: dosage and price

October 25th, 2007

As with all prescription drugs, proper dosage is at the discretion of a licensed medical doctor. The dose of sildenafil is 25 mg to 100 mg taken once per day between 30 minutes and 4 hours prior to sexual intercourse.

It is usually recommended to start with a dosage of 50 mg and then lower or [...]

PDE5 inhibitors as treatment of impotence

October 25th, 2007

Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer’s Sandwich, Kent research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease).

Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little [...]

Generic Viagra

December 24th, 2006

Generic Viagra (sildenafil citrate) contains the same active ingredients used in Pfizer Pharmaceutical’s Viagra®.
Viagra is an oral medication for the treatment of male impotence.
Impotence (or erectile dysfunction) is defined as the inability to achieve or maintain an erection sufficient for sexual intercourse, and includes the inability to get an erection as a result of sexual [...]

Side Effects of LEVITRA

December 23rd, 2006

LEVITRA is effective and well tolerated. Its side effects are generally mild and do not last very long.
Do not take LEVITRA if:

You take any form of medication known as “nitrates” (a type of medicine used to relieve chest pain that can occur as a result of heart disease) or recreational drugs called “poppers” like amyl [...]

LEVITRA help you get a quality erection

December 23rd, 2006

Currently, there is no cure for erectile dysfunction (ED), but LEVITRA may be able to help you get and keep a quality erection so that you can make the most of each sexual experience. You may notice improvements in both erection hardness and your ability to maintain your erection during sex.
Of course, LEVITRA alone will [...]

How Does LEVITRA Work?

December 23rd, 2006

LEVITRA belongs to a class of drugs called “PDE5 inhibitors.” It works by increasing blood flow to the penis to improve erectile function. The active ingredient in LEVITRA works specifically on the chain of events that occurs in the penis during arousal, when two large chambers in a man’s penis fill with blood.
In clinical trials, [...]

Levitra

December 23rd, 2006

LEVITRA is an FDA-approved oral prescription medication for the treatment of erectile dysfunction (ED) in men. It is available in 2.5-mg, 5-mg, 10-mg, and 20-mg tablets and is taken only when needed. Take LEVITRA no more than once a day.
What LEVITRA does:

LEVITRA helps increase blood flow to the penis, so it may help men with [...]

The side effects with CIALIS

December 23rd, 2006

Like all medications, CIALIS may have some side effects. The most common side effects with CIALIS are headache, upset stomach, back pain, and muscle aches. These side effects usually go away after a few hours. Patients who get back pain and muscle aches usually get it 12 to 24 hours after taking CIALIS. Back pain [...]

Cialis Work

December 23rd, 2006

CIALIS helps increase blood flow in the penis when a man is sexually stimulated.
CIALIS can help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.
CIALIS is clinically proven to improve erectile function in most [...]

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