Mechanism of Cialis action

October 25th, 2007

 
Although Viagra, Levitra, and Cialis all work by inhibition of PDE5, tadalafil’s distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the “weekend pill.” This longer half-life also [...]

Viagra: dosage and price

October 25th, 2007

As with all prescription drugs, proper dosage is at the discretion of a licensed medical doctor. The dose of sildenafil is 25 mg to 100 mg taken once per day between 30 minutes and 4 hours prior to sexual intercourse.

It is usually recommended to start with a dosage of 50 mg and then lower or [...]

PDE5 inhibitors as treatment of impotence

October 25th, 2007

Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer’s Sandwich, Kent research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease).

Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little [...]

Testosterone and Erection

April 1st, 2007

Though it is difficult to say precisely what part testosterone plays in helping to produce erections, it certainly both primes the penis and triggers the chain of events which bring an erection about. It is surprising, but gratifying, how often when adequate testosterone therapy is given, all the symptoms of the andropause disappear within a [...]

Erection-inducing drugs

April 1st, 2007

Oral drugs which induce erection have revolutionised the treatment of ED over the last eight years. They don’t work for everybody, but they do work for the majority – even in diabetes. They can also help people with neurological and spinal problems.
Also, the choice of available drugs means that if one particular drug doesn’t suit [...]

Impotence vacuum pump

December 24th, 2006

Prior to the launch of Viagra®, the little blue pill that revolutionized the treatment of male impotence, impotence vacuum pumps were one of the most popular and successful impotence treatments available.

Impotence vacuum pumps remain the preferable option and the most viable alternative to the new impotence drugs for a large number of men.
Impotence (or erectile [...]

Generic Viagra

December 24th, 2006

Generic Viagra (sildenafil citrate) contains the same active ingredients used in Pfizer Pharmaceutical’s Viagra®.
Viagra is an oral medication for the treatment of male impotence.
Impotence (or erectile dysfunction) is defined as the inability to achieve or maintain an erection sufficient for sexual intercourse, and includes the inability to get an erection as a result of sexual [...]

Erection-inducing drugs

December 24th, 2006

Oral drugs which induce erection have revolutionised the treatment of ED over the last seven years. They don’t work for everybody, but they do work for the majority – even in diabetes. They can also help people with neurological and spinal problems.
Also, the choice of available drugs means that if one particular drug doesn’t suit [...]

Sexual Impotence Treatment

December 23rd, 2006

Most physicians suggest that treatments proceed from least to most invasive. For some men, making a few healthy lifestyle changes may solve the problem. Quitting smoking, losing excess weight, and increasing physical activity may help some men regain sexual function.
Cutting back on any drugs with harmful side effects is considered next. For example, drugs for [...]

Erectile dysfunction

December 23rd, 2006

Erectile dysfunction, sometimes called “impotence,” is the repeated inability to get or keep an erection firm enough for sexual intercourse. The word “impotence” may also be used to describe other problems that interfere with sexual intercourse and reproduction, such as lack of sexual desire and problems with ejaculation or orgasm. Using the term erectile dysfunction [...]

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